News

Edition 7, November 2015

NEWS

KYROBIO Final Webinar - Key Findings	University of Stuttgart Update	Johnson Matthey Update
KYROBIO are currently preparing for the last in their series of webinars. The end of project webinar will focus on key findings and technology developments. It will be made accessible on the KYROBIO website shortly and a notification will be sent out once it is available to view.	Natural squalene hopene cyclases (SHCs) catalyze a sophisticated polycyclization reaction cascade that is started from the symmetrical substrate squalene to the products hopene and hopanol. This cyclization reaction is one of the most complex reactions known in biochemistry and reveals the incomparable high selectivity that can be obtained by performing reactions in enzyme´s active sites. The team of Prof. Bernhard Hauer at the Institute of Technical Biochemistry at the Universitaet Stuttgart, Germany used functionalized acyclic terpene derivatives as substrates for SHCs which enable the syntheses of numerous non-natural carbopolycyclic and heteropolycyclic products in a stereoselective manner. Read more>>	A successful case study of an engineered transaminase mutant for bulky-bulky ketones generated during the KYROBIO project was presented at the Enzyme Engineering Conference XXIII. The case study was set in the context of the general strategy of engineering followed in-house at Johnson Matthey. Did you know... Various mutant libraries, which were generated as part of KYROBIO, are now directly available for use in screening for customer projects. Contact ursula.schell@matthey.com

University of Manchester Update

Austrian Chemistry Days - TU Graz

Final Consortium Meeting

KYROBIO work in Manchester acknowledged in leading journals - JACS, Angewandte & ACS Catalysis
Researchers at Manchester contribute to coordination and delivery of planned MOOC in Industrial Biotechnology
Presentations by Manchester researchers highlight KYROBIO work to young researchers and the general public

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Dr. Margit Winkler, Senior researcher at the Austrian Centre of Industrial Biotechnology, recently presented at the Austrian Chemistry Days. This year, the Austrian Chemistry days were hosted as a joint meeting of the Italian & Austrian Chemical Societies. With our long tradition in Graz to discover, study and engineer hydroxynitrile lyases for industrial application we were delighted to present a totally new enzyme. After the talk by Margit Winkler, several researchers were approached for more details and to discuss potential collaborations.

The final Kyrobio Consortium Meeting took place at The University of Stuttgart where project partners presented progress in the project, and results achieved. Actions for the final three months of the project were agreed with a focus on maximising impact from the project.

UPCOMING EVENTS

ICB 2016: 18th International Conference on Biocatalysis

3rd meeting on Applied Synthetic Biology in Europe

5th International Conference on Industrial Biotechnology

Date: 15 to 16 February 2016 | Venue: Barcelona, Spain

The ICB 2016: 18th International Conference on Biocatalysis aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results about all aspects of Biocatalysis. It also provides the premier interdisciplinary forum for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns, practical challenges encountered and the solutions adopted in the field of Biocatalysis.